In ooreenstemming met REACH-regulasies, voordat toetse onder Bylae IX en X uitgevoer word (vir registrasievolumes van 100-1000 ton per jaar en meer as 1000 ton per jaar), moet geregistreerde 'n toetsvoorstel (TP) indien. Na 'n konsultasietydperk sal ECHA die toetsvereistes finaliseer op grond van terugvoer en die eienskappe van die stof.
On May 14, 2024, the European Chemicals Agency (ECHA) announced 12 new substance testing proposals and invited the public to submit their comments by following dates.
ECHA’s public consultation on substance testing proposals is a transparent process to determine if additional testing is needed for chemical registration dossiers to ensure safety. This process gathers input from various stakeholders to improve chemical safety assessments. After the consultation period, ECHA will adjust the testing requirements based on the feedback. Registrants must then conduct the specified tests, submit the results, and update their safety documentation to ensure safe use and promote industry sustainability.
| Naam | EC Num./ CAS Num. | Hazard endpoint for which vertebrate testing was proposed | Deadline for submitting information |
| 4,4′-methylenebis[N,N-bis(2,3-epoxypropyl)aniline] | 249-204-3 28768-32-3 | 6.1.2 Long-term toxicity to fish | 27/05/2024 |
| Dibroommetaan | 200-824-2 74-95-3 | 7.6.2 Genetic toxicity in vivo | 27/05/2024 |
| Diethyl suksineer | 204-612-0 123-25-1 | 7.5.1 Repeated dose toxicity: oral 7.8.2 Developmental toxicity / teratogenicity | 27/05/2024 |
| Manganate(1-), glycinato-N,O)[sulfato(2-)-O]-, hydrogen | 838-538-0 52139-31-8 | 7.6.2 Genetic toxicity in vivo | 27/05/2024 |
| menthol | 201-939-0 89-78-1 | 6.1.2 Long-term toxicity to fish | 28/06/2024 |
| N,N-dimethylacrylamide | 220-237-5 2680-03-7 | 7.8.2 Developmental toxicity / teratogenicity | 28/06/2024 |
| N-(2-(dimethylamino)ethoxy)ethyl)-N-methyl-1,3-propanediamine | 470-720-1 189253-72-3 | 7.5.1 Repeated dose toxicity: oral 7.8.2 Developmental toxicity / teratogenicity | 27/05/2024 |
| N-[3-(dimethylamino)propyl] C6-9 alkyl amides | 948-134-7 - | 6.1.2 Long-term toxicity to fish | 28/06/2024 |
| Polyhydroxy-N,N-polyalkylbenzene-polycarboxamide | - - | 7.5.1 Repeated dose toxicity: oral 7.8.2 Developmental toxicity / teratogenicity | 27/05/2024 |
| Sodium chlorite | 231-836-6 7758-19-2 | 6.1.2 Long-term toxicity to fish 7.6.2 Genetic toxicity in vivo | 28/06/2024 |
| Tetrametielammoniumhidroksied | 200-882-9 75-59-2 | 7.8.2 Developmental toxicity / teratogenicity||Note: testing proposed with Tetramethyl ammonium chloride (EC no. 200-880-8) | 28/06/2024 |
| Triisobutyl phosphate | 204-798-3 126-71-6 | 6.1.2 Long-term toxicity to fish | 27/05/2024 |
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